EGFR 3′UTR 774T>C polymorphism contributes to bladder cancer risk
نویسندگان
چکیده
منابع مشابه
PSCA rs2294008 C > T polymorphism contributes to gastric and bladder cancer risk
BACKGROUND Previous studies suggested genetic variations in PSCA (prostate stem cell antigen) may confer the susceptibility of cancer. Many case-control studies have reported the relationship between PSCA rs2294008 C > T polymorphism and cancer, especially gastric cancer and bladder cancer. However, the results are inconsistent. This meta-analysis is aimed at evaluating the association of rs229...
متن کاملRs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis
Objective(s):Genome-wide association studies have identified a number of genetic variants of telomerase reverse transcriptase (TERT), cleft lip and palate transmembrane1-like (CLPTM1L) associated with the risk of bladder cancer. Rs401681 polymorphism in TERT-CLPTM1L was of special interest for bladder cancer risk, whereas the results were inconclusive. Materials and Methods:Publications illustr...
متن کاملGenetic polymorphism intermingled with environmental factors substantially contributes to the bladder cancer progression
Bladder cancer is a common issue in urological practice. The tumor originates in urothelium – an internal epithelial lining of urinary bladder. Hence, the urothelium is exposed to numerous pathogens excreted in urine, natural as well as synthetic compounds such as: bacteria, viruses, hormones, drug metabolites, salts, and xenobiotic toxins (aromatic amines, polycyclic aromatic hydrocarbons, oth...
متن کاملGenetic polymorphism in bladder cancer.
Individual variation in the genetic constitution of humans may affect the host responses to constant assaults from exogenous and endogenous carcinogens, which will eventually impact cancer risk, disease prognosis and clinical outcome. Bladder cancer is one of the most common cancers in the world. In this review, the published research articles studying the association between genetic polymorphi...
متن کاملSTAT3 and STAT5b polymorphism contributes to breast cancer risk and clinical outcomes.
We conducted a case-control study in a Chinese population, and investigated the role of STAT3 rs4796793 and STAT5b rs6503691 polymorphisms in the risk and clinical outcome of breast cancer. STAT5b rs6503691 polymorphisms and STAT3 rs4796793 polymorphisms were genotyped by TaqMan SNP Genotyping Assays on the ABI 7500 fast real-time PCR platform. Unconditional logistic regression analyses showed ...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2012
ISSN: 1464-3804,0267-8357
DOI: 10.1093/mutage/ges051